The Mysterious Unfoldome: Structureless, Underappreciated, Yet Vital Part of Any Given Proteome

Contrarily to the general believe, many biologically active proteins lack stable tertiary and/or secondary structure under physiological conditions in vitro. These intrinsically disordered proteins (IDPs) are highly abundant in nature and many of them are associated with various human diseases. The...

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Bibliographic Details
Main Author: Vladimir N. Uversky
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/568068