Chronic intracerebroventricular administration of dimethyl sulfoxide attenuates streptozotocin-iduced memory loss in rats

Background: The memory impairment, obtained from intracerebroventricular (i.c.v.) infusion of streptozotocin (STZ) in rats through activation of oxidative stress, is accepted as sporadic Alzheimer’s disease (AD) model in most experimental studies. Dimethyl sulfoxide (DMSO) as a solvent is widely use...

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Bibliographic Details
Main Authors: Esmaeil Akbari, Nima Naderi, Keyvan Yaghoobi, Behzad Parsi, Sahar Berijani
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences and Health Services 2013-02-01
Series:Research in Molecular Medicine
Subjects:
Online Access:http://rmm.mazums.ac.ir/browse.php?a_code=A-10-26-3&slc_lang=en&sid=1