Chronic intracerebroventricular administration of dimethyl sulfoxide attenuates streptozotocin-iduced memory loss in rats
Background: The memory impairment, obtained from intracerebroventricular (i.c.v.) infusion of streptozotocin (STZ) in rats through activation of oxidative stress, is accepted as sporadic Alzheimer’s disease (AD) model in most experimental studies. Dimethyl sulfoxide (DMSO) as a solvent is widely use...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Mazandaran University of Medical Sciences and Health Services
2013-02-01
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Series: | Research in Molecular Medicine |
Subjects: | |
Online Access: | http://rmm.mazums.ac.ir/browse.php?a_code=A-10-26-3&slc_lang=en&sid=1 |