BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells

<p>Abstract</p> <p>Background</p> <p>BAK (Bcl-2 homologous antagonist/killer) is a novel pro-apoptotic gene of the Bcl-2 family. It has been reported that gastric tumors have reduced BAK levels when compared with the normal mucosa. Moreover, mutations of the BAK gene ha...

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Bibliographic Details
Main Authors: Liu Jun, Wang Liang, Zheng Li-Duan, Tong Qiang-Song, Qian Wei
Format: Article
Language:English
Published: BMC 2004-07-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/4/33