Lethal mutants and truncated selection together solve a paradox of the origin of life.

BACKGROUND: Many attempts have been made to describe the origin of life, one of which is Eigen's cycle of autocatalytic reactions [Eigen M (1971) Naturwissenschaften 58, 465-523], in which primordial life molecules are replicated with limited accuracy through autocatalytic reactions. For succes...

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Bibliographic Details
Main Authors: David B Saakian, Christof K Biebricher, Chin-Kun Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3144202?pdf=render