SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway

SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway

Non-syndromic cleft lip and palate (NSCLP) is one of the most common congenital malformations with multifactorial etiology. Although long non-coding RNAs (lncRNAs) have been implicated in the development of lip and palate, their roles in NSCLP are not fully elucidated. This study aimed to investigat...

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Bibliographic Details
Main Authors: Shiyu Chen, Zhonglin Jia, Ming Cai, Mujie Ye, Dandan Wu, Teng Wan, Bowen Zhang, Peixuan Wu, Yuexin Xu, Yuntao Guo, Chan Tian, Duan Ma, Jing Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NSCLP
ZFAS1
Sp1
CTCF
Wnt/β-catenin pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.662780/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.662780/full

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