Pharmacokinetics, tissue distribution and excretion of luteolin and its major metabolites in rats: Metabolites predominate in blood, tissues and are mainly excreted via bile
To elucidate the in vivo bioactivities of luteolin, an important food-derived flavonoid, its metabolic fate and pharmacokinetic properties in rats were investigated. Total of 8 metabolites were isolated from urine and bile and identified by NMR. Luteolin was firstly metabolized via either glucuronid...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-08-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464617303079 |