Regulation of ryanodine receptor RyR2 by protein-protein interactions: prediction of a PKA binding site on the N-terminal domain of RyR2 and its relation to disease causing mutations [v1; ref status: indexed, http://f1000r.es/4tw]

Protein-protein interactions are the key processes responsible for signaling and function in complex networks. Determining the correct binding partners and predicting the ligand binding sites in the absence of experimental data require predictive models. Hybrid models that combine quantitative atomi...

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Bibliographic Details
Main Authors: Belinda Nazan Walpoth, Burak Erman
Format: Article
Language:English
Published: F1000 Research Ltd 2015-01-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-29/v1