Hypoxia-regulated target genes implicated in tumor metastasis

Hypoxia-regulated target genes implicated in tumor metastasis

<p>Abstract</p> <p>Hypoxia is an important microenvironmental factor that induces cancer metastasis. Hypoxia/hypoxia-inducible factor-1α (HIF-1α) regulates many important steps of the metastatic processes, especially epithelial-mesenchymal transition (EMT) that is one of the crucia...

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Bibliographic Details
Main Authors: Tsai Ya-Ping, Wu Kou-Juey
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Biomedical Science
Subjects:
Hypoxia
Hypoxia-inducible factor
Target genes
Metastasis
Epithelial-mesenchymal transition
Online Access:http://www.jbiomedsci.com/content/19/1/102

Internet

http://www.jbiomedsci.com/content/19/1/102

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