Rapid detection of dendritic cell and monocyte disorders using CD4 as a lineage marker of the human peripheral blood antigen presenting cell compartment

Dendritic cells (DCs) and monocytes are critical regulators and effectors of innate and adaptive immune responses. Monocyte expansion has been described in many pathological states while monocyte and DC deficiency syndromes are relatively recent additions to the catalogue of human primary immunodef...

Full description

Bibliographic Details
Main Authors: Laura eJardine, Dawn eBarge, Ashley eAmes-Draycott, Sarah ePagan, Sharon eCookson, Gavin eSpickett, Muzlifah eHaniffa, Matthew eCollin, Venetia eBigley
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
CD4
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00495/full