Chemical synthesis, docking studies and biological effects of functionalized 1,3-diaryl-2-propen-1-ones on human colon cancer cells

A series of 1, 3-diaryl-2-propen-1-ones was synthesised in order to obtain a new type of anticancer drug, designed with hybrid features to inhibit colon cancer activated receptor. Based on computational modelling and docking studies, potential inhibitors were synthesised and their biological activi...

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Bibliographic Details
Main Authors: Guo-Min Zhu, Guo-Dong Huang
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2015-03-01
Series:Bangladesh Journal of Pharmacology
Subjects:
1
Online Access:https://www.banglajol.info/index.php/BJP/article/view/21699