Chemical synthesis, docking studies and biological effects of functionalized 1,3-diaryl-2-propen-1-ones on human colon cancer cells
A series of 1, 3-diaryl-2-propen-1-ones was synthesised in order to obtain a new type of anticancer drug, designed with hybrid features to inhibit colon cancer activated receptor. Based on computational modelling and docking studies, potential inhibitors were synthesised and their biological activi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Bangladesh Pharmacological Society
2015-03-01
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Series: | Bangladesh Journal of Pharmacology |
Subjects: | |
Online Access: | https://www.banglajol.info/index.php/BJP/article/view/21699 |