Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes

Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes

Obese women with type 2 diabetes mellitus (T2DM) have more inflammation in their subcutaneous white adipose tissue (sWAT) than age-and-BMI similar obese women with normal glucose tolerance (NGT). We aimed to investigate whether WAT fatty acids and/or oxylipins are associated with the enhanced inflam...

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Bibliographic Details
Main Authors: Mattijs M. Heemskerk, Martin Giera, Fatiha el Bouazzaoui, Mirjam A. Lips, Hanno Pijl, Ko Willems van Dijk, Vanessa van Harmelen
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Nutrients
Subjects:
leukotrienes
arachidonic acid
omega-3 fatty acids
lipidomics
gene expression
Online Access:http://www.mdpi.com/2072-6643/7/9/5362

Internet

http://www.mdpi.com/2072-6643/7/9/5362

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