Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD<sup>+/- </sup>mice

Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD<sup>+/- </sup>mice

<p>Abstract</p> <p>Background</p> <p>Chronic therapy with nitroglycerin (GTN) results in a rapid development of nitrate tolerance which is associated with an increased production of reactive oxygen species (ROS). According to recent studies, mitochondrial ROS formation...

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Bibliographic Details
Main Authors: Stalleicken Dirk, Reifenberg Kurt, Schuhmacher Swenja, Schulz Eberhard, Pautz Andrea, Treiber Nicolai, Oelze Matthias, Wenzel Philip, Mollnau Hanke, Scharffetter-Kochanek Karin, Kleinert Hartmut, Münzel Thomas, Daiber Andreas
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Cardiovascular Disorders
Online Access:http://www.biomedcentral.com/1471-2261/6/44

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http://www.biomedcentral.com/1471-2261/6/44

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