Systematic Analysis of Drug Vulnerabilities Conferred by Tumor Suppressor Loss

Systematic Analysis of Drug Vulnerabilities Conferred by Tumor Suppressor Loss

Summary: In addition to oncogene inhibition, targeting tumor suppressor deficiency could provide potential venues for precision cancer medicine. However, the full spectrum of drug vulnerability conferred by tumor suppressor loss remains unclear. We systematically analyzed how loss of 59 common tumor...

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Bibliographic Details
Main Authors: Hongyu Ding, Jie Zhao, Yanli Zhang, Jiao Yu, Mingxian Liu, Xiaoxi Li, Liang Xu, Minghui Lin, Chuan Liu, Zhengjin He, Shishuang Chen, Hai Jiang
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719306631

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http://www.sciencedirect.com/science/article/pii/S2211124719306631

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