Regulation of T cell antitumor immune response by tumor induced metabolic stress

Adaptive T cell immune response is essential for tumor growth control. The efficacy of immune checkpoint inhibitors is regulated by intratumoral immune response. The tumor microenvironment has a major role in adaptive immune response tuning. Tumor cells generate a particular metabolic environment in...

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Bibliographic Details
Main Authors: Fanny Chalmin, Mélanie Bruchard, Frederique Vegran, Francois Ghiringhelli
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-11-01
Series:Cell Stress
Subjects:
Online Access:http://www.cell-stress.com/researcharticles/2019a-chalmin-cell-stress/