A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation
<p>Abstract</p> <p>Background</p> <p>Alterations in multiple cellular pathways contribute to the development of chronic neurodegeneration such as a sporadic Alzheimer's disease (AD). These, in turn, involve changes in gene expression, amongst which are genes regula...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-02-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/3/1/4 |