Staphylococcus aureus with an erm-mediated constitutive macrolide-lincosamide-streptogramin B resistance phenotype has reduced susceptibility to the new ketolide, solithromycin

Staphylococcus aureus with an erm-mediated constitutive macrolide-lincosamide-streptogramin B resistance phenotype has reduced susceptibility to the new ketolide, solithromycin

Abstract Background Solithromycin, the fourth generation of ketolides, has been demonstrated potent antibacterial effect against commonly-isolated gram-positive strains. However, Staphylococcus aureus (S. aureus) strains with a higher solithromycin MIC have already been emerged, the mechanism of whi...

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Bibliographic Details
Main Authors: Weiming Yao, Guangjian Xu, Duoyun Li, Bing Bai, Hongyan Wang, Hang Cheng, Jinxin Zheng, Xiang Sun, Zhiwei Lin, Qiwen Deng, Zhijian Yu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Infectious Diseases
Subjects:
Staphylococcus aureus
Constitutive macrolide-lincosamide-streptogramin B (cMLSB) resistance
Solithromycin
Online Access:http://link.springer.com/article/10.1186/s12879-019-3779-8

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http://link.springer.com/article/10.1186/s12879-019-3779-8

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