Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemia

Sirtuin1 (Sirt1) and Sirtuin3 (Sirt3) are two well-characterized members of the silent information regulator 2 (Sir2) family of proteins. Both Sirt1 and Sirt3 have been shown to play vital roles in resistance to cellular stress, but the interaction between these two sirtuins has not been fully deter...

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Bibliographic Details
Main Authors: Tao Chen, Shu-Hui Dai, Xia Li, Peng Luo, Jie Zhu, Yu-Hai Wang, Zhou Fei, Xiao-Fan Jiang
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717304561