Lgr5 maintains stemness and regulates cell property in nasopharyngeal carcinoma through Wnt/β-catenin signaling pathway

Lgr5 maintains stemness and regulates cell property in nasopharyngeal carcinoma through Wnt/β-catenin signaling pathway

Nasopharyngeal carcinoma (NPC) is a common malignant tumor in Southern China and Southeast Asia. In this study, we found that Leucine rich repeat containing G protein-coupled receptor 5 (Lgr5) was highly expressed in NPC tissues and marked NPC stem cells. Lgr5high tumors showed differential transcri...

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Bibliographic Details
Main Authors: Fangqi Li, Xiaole Song, Xuewen Li, Xiujuan Zhang, Xiaoyu Feng, Li Wang, Lun Xu, Jiqin Luo, Bijun Zhu, Wenwen Ren, Hongmeng Yu, Yiqun Yu
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Stem Cell Research
Subjects:
Lgr5
Nasopharyngeal carcinoma
Stem cells
Epithelial-mesenchymal transition
Wnt/β-catenin pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120302178

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http://www.sciencedirect.com/science/article/pii/S1873506120302178

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