Hypothesis for a mechanism of beam-induced motion in cryo-electron microscopy

Estimates of heat-transfer rates during plunge-cooling and the patterns of ice observed in cryo-EM samples indicate that the grid bars cool much more slowly than do the support foil and sample near the middle of the grid openings. The resulting transient temperature differences generate transient te...

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Bibliographic Details
Main Author: Robert E. Thorne
Format: Article
Language:English
Published: International Union of Crystallography 2020-05-01
Series:IUCrJ
Subjects:
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252520002560