Retention and loss of RNA interference pathways in trypanosomatid protozoans.

RNA interference (RNAi) pathways are widespread in metaozoans but the genes required show variable occurrence or activity in eukaryotic microbes, including many pathogens. While some Leishmania lack RNAi activity and Argonaute or Dicer genes, we show that Leishmania braziliensis and other species wi...

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Bibliographic Details
Main Authors: Lon-Fye Lye, Katherine Owens, Huafang Shi, Silvane M F Murta, Ana Carolina Vieira, Salvatore J Turco, Christian Tschudi, Elisabetta Ullu, Stephen M Beverley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2965760?pdf=render