Base Flipping in Open Complex Formation at Bacterial Promoters

In the process of transcription initiation, the bacterial RNA polymerase binds double-stranded (ds) promoter DNA and subsequently effects strand separation of 12 to 14 base pairs (bp), including the start site of transcription, to form the so-called “open complex” (also referred to as RPo). This com...

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Bibliographic Details
Main Authors: Mary E. Karpen, Pieter L. deHaseth
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/5/2/668