Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma

A simple, fast, and cost-effective LC-MS/MS method for quantification of rifampicin in human plasma was developed and fully validated. The plasma samples containing rifampicin and isotopically labelled internal standard rifampicin D8, were cleaned up using a Captiva ND Lipids filtration plate. Chrom...

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Bibliographic Details
Main Authors: Žane Temova Rakuša, Robert Roškar, Anita Klančar Andrejc, Tina Trdan Lušin, Nataša Faganeli, Iztok Grabnar, Aleš Mrhar, Albin Kristl, Jurij Trontelj
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2019/4848236