Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight.

The insulin-like growth factor 2 receptor (IGF2R) is essential for prenatal growth regulation and shows gene dosage effects on fetal weight that can be affected by in-vitro embryo culture. Imprinted maternal expression of murine Igf2r is well documented for all fetal tissues excluding brain, but pol...

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Main Authors: Daniela Bebbere, Stefan Bauersachs, Rainer W Fürst, Horst-Dieter Reichenbach, Myriam Reichenbach, Ivica Medugorac, Susanne E Ulbrich, Eckhard Wolf, Sergio Ledda, Stefan Hiendleder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620161?pdf=render