Generation of iPSC lines from primary human chorionic villi cells

Primary human chorionic villi (CV) cells were used to generate the iPSC line by retroviral transduction of the four Yamanaka-factors OCT4, SOX2, KLF4 and c-MYC. Pluripotency was confirmed both in vivo and in vitro. The transcriptomes of the CV-derived iPSC lines and the human embryonic stem cell lin...

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Bibliographic Details
Main Authors: Björn Lichtner, Peggy Matz, James Adjaye
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115001464