Antiproliferative Effects of Epigenetic Modifier Drugs through E-cadherin Up-regulation in Liver Cancer Cell Lines

Antiproliferative Effects of Epigenetic Modifier Drugs through E-cadherin Up-regulation in Liver Cancer Cell Lines

Introduction and aim. Epigenetic alterations play an essential role in cancer onset and progression, thus studies of drugs targeting the epigenetic machinery are a principal concern for cancer treatment. Here, we evaluated the potential of the DNA methyltransferase inhibitor 5-aza-2’-deoxycytidine (...

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Bibliographic Details
Main Authors: Diego Uribe, Andres Cardona, Davide Degli Esposti, Marie-Pierre Cros, Cyrille Cuenin, Zdenko Herceg, Mauricio Camargo, Fabian M. Cortés-Mancera
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Annals of Hepatology
Subjects:
Liver cancer
DNA methylation
E-cadherin
5aza-dC
TSA
Wnt pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119302005

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http://www.sciencedirect.com/science/article/pii/S1665268119302005

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