Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes.

During sepsis, liver dysfunction is common, and failure of mitochondria to effectively couple oxygen consumption with energy production has been described. In addition to sepsis, pharmacological agents used to treat septic patients may contribute to mitochondrial dysfunction. This study addressed th...

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Bibliographic Details
Main Authors: Siamak Djafarzadeh, Madhusudanarao Vuda, Jukka Takala, Stephan M Jakob
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3441687?pdf=render