Tumorigenicity Testing in Athymic Mice of Cultured Human Melanocytes for Transplantation in Engineered Skin Substitutes

Autologous engineered skin substitutes (ESS) have been shown to close excised, full-thickness burns, but are consistently hypopigmented due to depletion of human melanocytes (hM) during culture of keratinocytes. Hypothetically, addition of hM to ESS may restore uniform pigmentation, but may also pro...

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Bibliographic Details
Main Authors: Steven T. Boyce Ph.D., Rachel L. Zimmerman, Dorothy M. Supp
Format: Article
Language:English
Published: SAGE Publishing 2015-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368914X683052