Tumorigenicity Testing in Athymic Mice of Cultured Human Melanocytes for Transplantation in Engineered Skin Substitutes
Autologous engineered skin substitutes (ESS) have been shown to close excised, full-thickness burns, but are consistently hypopigmented due to depletion of human melanocytes (hM) during culture of keratinocytes. Hypothetically, addition of hM to ESS may restore uniform pigmentation, but may also pro...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-08-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368914X683052 |