Effect of Antioxidants on the Fibroblast Replicative Lifespan In Vitro

Replicative senescence is an unalterable growth arrest of primary cells in the culture system. It has been reported that aging in vivo is related to the limited replicative capacity that normal somatic cells show in vitro. If oxidative damage contributes to the lifespan limitation, antioxidants are...

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Bibliographic Details
Main Authors: Izabela Sadowska-Bartosz, Grzegorz Bartosz
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/6423783