Fusion of single-cell transcriptome and DNA-binding data, for genomic network inference in cortical development

Abstract Background Network models are well-established as very useful computational-statistical tools in cell biology. However, a genomic network model based only on gene expression data can, by definition, only infer gene co-expression networks. Hence, in order to infer gene regulatory patterns, i...

Full description

Bibliographic Details
Main Author: Thomas Bartlett
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04201-9