Suppression of autoimmune retinal inflammation by an antiangiogenic drug.

Chronic and recurrent uveitis account for approximately 10% of legal blindness in the western world. Autoimmune uveitis is driven by activated CD4(+) T cells that differentiate into effector T helper cells (Th1, Th2, and Th17) which release proinflammatory cytokines that damage the retina. In this s...

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Bibliographic Details
Main Authors: Takeru Yoshimura, Ofra Benny, Lauren Bazinet, Robert J D'Amato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681944?pdf=render