Impact of hormone-associated resistance to activated protein C on the thrombotic potential of oral contraceptives: a prospective observational study.

The increased thrombotic risk of oral contraceptives (OC) has been attributed to various alterations of the hemostatic system, including acquired resistance to activated protein C (APC). To evaluate to what extent OC-associated APC resistance induces a prothrombotic state we monitored plasma levels...

Full description

Bibliographic Details
Main Authors: Heiko Rühl, Lars Schröder, Jens Müller, Shorena Sukhitashvili, Julia Welz, Walther C Kuhn, Johannes Oldenburg, Christian Rudlowski, Bernd Pötzsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4133351?pdf=render