Broadly active zinc finger protein-guided transcriptional activation of HIV-1

Broadly active zinc finger protein-guided transcriptional activation of HIV-1

Human immunodeficiency virus type 1 (HIV-1) causes a persistent viral infection resulting in the demise of immune regulatory cells. Clearance of HIV-1 infection results in integration of proviral DNA into the genome of host cells, which provides a means for evasion and long-term persistence. A thera...

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Bibliographic Details
Main Authors: Tristan A. Scott, Denis O’Meally, Nicole Anne Grepo, Citradewi Soemardy, Daniel C. Lazar, Yue Zheng, Marc S. Weinberg, Vicente Planelles, Kevin V. Morris
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
HIV-1
transcription
zinc finger protein
ZFN-362-VPR
activation
latency
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120302229

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http://www.sciencedirect.com/science/article/pii/S2329050120302229

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