Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.

Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.

Escherichia coli AlkB is a 2-oxoglutarate- and iron-dependent dioxygenase that reverses alkylated DNA damage by oxidative demethylation. Mouse AlkB homolog 1 (Alkbh1) is one of eight members of the newly discovered family of mammalian dioxygenases.In the present study we show non-Mendelian inheritan...

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Bibliographic Details
Main Authors: Line M Nordstrand, Jessica Svärd, Elisabeth Larsen, Anja Nilsen, Rune Ougland, Kari Furu, Guro F Lien, Torbjørn Rognes, Satoshi H Namekawa, Jeannie T Lee, Arne Klungland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2972218?pdf=render

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http://europepmc.org/articles/PMC2972218?pdf=render

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