A Peptide Inhibitor of Peroxiredoxin 6 Phospholipase A<sub>2</sub> Activity Significantly Protects against Lung Injury in a Mouse Model of Ventilator Induced Lung Injury (VILI)

Ventilator induced lung injury (VILI) is a lung injury syndrome associated with mechanical ventilation, most frequently for treatment of Acute Lung Injury (ALI), and generally secondary to the use of greater than physiologic tidal volumes. To reproduce this syndrome experimentally, C57Bl/6 mice were...

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Bibliographic Details
Main Authors: Aron B. Fisher, Chandra Dodia, Shampa Chatterjee
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/6/925