Detection of homolog-independent meiotic DNA repair events in C. elegans with the intersister/intrachromatid repair assay

Summary: Accurate repair of DNA double-strand breaks (DSBs) in developing germ cells is critical to promote proper chromosome segregation and to maintain genome integrity. To directly detect homolog-independent (intersister/intrachromatid) meiotic DSB repair, we exploited the genetics and germline p...

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Bibliographic Details
Main Authors: Erik Toraason, Marissa Glover, Anna Horacek, Diana E. Libuda
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005074