A Depleting Anti-CD45 Monoclonal Antibody as Isolated Conditioning for Bone Marrow Transplantation in the Rat.

A Depleting Anti-CD45 Monoclonal Antibody as Isolated Conditioning for Bone Marrow Transplantation in the Rat.

OBJECTIVE:A monoclonal antibody (mAb) against the leukocyte common antigen CD45 (RT7 in rats) could facilitate bone marrow transplantation (BMT). This study in rats evaluates a depletive rat anti-RT7a mAb as isolated tool for BMT conditioning without using irradiation or any chemotherapeutic / immun...

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Bibliographic Details
Main Authors: Mark D Jäger, Florian W R Vondran, Wolf Ramackers, Tilmann Röseler, Hans J Schlitt, Hüseyin Bektas, Jürgen Klempnauer, Kai Timrott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4854389?pdf=render

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http://europepmc.org/articles/PMC4854389?pdf=render

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