Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers

Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers

Abstract Background Leukocyte telomere length (LTL) has been shown to predict Alzheimer’s disease (AD), albeit inconsistently. Failing to account for the competing risks between AD, other dementia types, and mortality, can be an explanation for the inconsistent findings in previous time-to-event ana...

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Bibliographic Details
Main Authors: Fernanda Schäfer Hackenhaar, Maria Josefsson, Annelie Nordin Adolfsson, Mattias Landfors, Karolina Kauppi, Magnus Hultdin, Rolf Adolfsson, Sofie Degerman, Sara Pudas
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Leukocyte telomere length
Dementia
Risk factors
Time-to-event analysis
Competing risks
Vascular dementia
Online Access:https://doi.org/10.1186/s13195-021-00871-y

Internet

https://doi.org/10.1186/s13195-021-00871-y

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