Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive decline in cognitive function associated with the neuropathological hallmarks amyloid β-peptide (Aβ) plaques and neurofibrillary tangles. Because aging is the major risk factor for AD, and dietary energy restr...

Full description

Bibliographic Details
Main Authors: Veerendra Kumar Madala Halagappa, Zhihong Guo, Michelle Pearson, Yasuji Matsuoka, Roy G. Cutler, Frank M. LaFerla, Mark P. Mattson
Format: Article
Language:English
Published: Elsevier 2007-04-01
Series:Neurobiology of Disease
Subjects:
Amyloid
Caloric restriction
Hippocampus
Learning and memory
Synaptic plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106003251

Internet

http://www.sciencedirect.com/science/article/pii/S0969996106003251

Similar Items