Complex Variant t(9;22) Chromosome Translocations in Five Cases of Chronic Myeloid Leukemia

The Philadelphia (Ph1) chromosome arising from the reciprocal t(9;22) translocation is found in more than 90% of chronic myeloid leukemia (CML) patients and results in the formation of the chimeric fusion gene BCR-ABL. However, a small proportion of patients with CML have simple or complex varia...

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Bibliographic Details
Main Authors: Ana Valencia, José Cervera, Esperanza Such, Eva Barragán, Pascual Bolufer, Oscar Fuster, Rosa Collado, Jesús Martínez, Miguel A. Sanz
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2009/187125