Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats

<p>Abstract</p> <p>Background</p> <p>CXCR4 is the receptor for chemokine CXCL12 and reportedly plays an important role in systemic vascular repair and remodeling, but the role of CXCR4 in development of pulmonary hypertension and vascular remodeling has not been fully u...

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Bibliographic Details
Main Authors: Hales Charles A, Yu Lunyin
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/21