Small Activating RNAs: Towards the Development of New Therapeutic Agents and Clinical Treatments

Small Activating RNAs: Towards the Development of New Therapeutic Agents and Clinical Treatments

Small double-strand RNA (dsRNA) molecules can activate endogenous genes via an RNA-based promoter targeting mechanism. RNA activation (RNAa) is an evolutionarily conserved mechanism present in diverse eukaryotic organisms ranging from nematodes to humans. Small activating RNAs (saRNAs) involved in R...

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Bibliographic Details
Main Authors: Hossein Ghanbarian, Shahin Aghamiri, Mohamad Eftekhary, Nicole Wagner, Kay-Dietrich Wagner
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
small interfering RNAs (siRNAs)
microRNAs (miRNAs)
small activating RNAs (saRNA)
molecular mechanism
neuronal development
cardiac development
Online Access:https://www.mdpi.com/2073-4409/10/3/591

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https://www.mdpi.com/2073-4409/10/3/591

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