Detection of the EGFR G719S Mutation in Non-small Cell Lung Cancer Using Droplet Digital PCR

Detection of the EGFR G719S Mutation in Non-small Cell Lung Cancer Using Droplet Digital PCR

Objectives: The main objectives of the study were (1) to set-up a droplet digital PCR (ddPCR) assay for the non-invasive detection of G719S EGFR mutation in NSCLC patients; (2) to determine the limits of detection of the ddPCR assay for G719S mutation and (3) to compare COBAS® and ddPCR System for G...

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Bibliographic Details
Main Authors: Margalida Esteva-Socias, Mónica Enver-Sumaya, Cristina Gómez-Bellvert, Mónica Guillot, Aitor Azkárate, Raquel Marsé, Úrsula Sastre, Ana Blasco, Silvia Calabuig-Fariñas, Víctor José Asensio, Josefa Terrasa, Antònia Obrador-Hevia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Medicine
Subjects:
EGFR
liquid biopsy
G719S
lung cancer
ddPCR = droplet digital PCR
non-small cell lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.594900/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.594900/full

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