Promoter hypermethylation of the <it>SFRP2 </it>gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer

<p>Abstract</p> <p>Background</p> <p>We have previously reported that expression of the Wnt antagonist genes <it>SFRP1 </it>and <it>SFRP5 </it>is frequently silenced by promoter hypermethylation in breast cancer. SFRP2 is a further Wnt inhibitor...

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Bibliographic Details
Main Authors: Knüchel Ruth, Hartmann Arndt, Jost Edgar, Bektas Nuran, Noetzel Erik, Veeck Jürgen, Dahl Edgar
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/83