Promoter hypermethylation of the <it>SFRP2 </it>gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer
<p>Abstract</p> <p>Background</p> <p>We have previously reported that expression of the Wnt antagonist genes <it>SFRP1 </it>and <it>SFRP5 </it>is frequently silenced by promoter hypermethylation in breast cancer. SFRP2 is a further Wnt inhibitor...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-11-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/7/1/83 |