Segmentation of Image Data from Complex Organotypic 3D Models of Cancer Tissues with Markov Random Fields.

Organotypic, three dimensional (3D) cell culture models of epithelial tumour types such as prostate cancer recapitulate key aspects of the architecture and histology of solid cancers. Morphometric analysis of multicellular 3D organoids is particularly important when additional components such as the...

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Bibliographic Details
Main Authors: Sean Robinson, Laurent Guyon, Jaakko Nevalainen, Mervi Toriseva, Malin Åkerfelt, Matthias Nees
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4668034?pdf=render