Molecular changes in pre-metastatic lymph nodes of esophageal cancer patients.

Lymph node metastasis indicates poor prognosis in esophageal cancer. To understand the underlying mechanisms, most studies so far focused on investigating the tumors themselves and/or invaded lymph nodes. However they neglected the potential events within the metastatic niche, which precede invasion...

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Bibliographic Details
Main Authors: Benjamin Otto, Alexandra M Koenig, Genrich V Tolstonog, Anke Jeschke, Kristin Klaetschke, Yogesh K Vashist, Daniel Wicklein, Christoph Wagener, Jakob R Izbicki, Thomas Streichert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105535?pdf=render