Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Luteolin is a 3',4',5,7-tetrahydroxyflavone found in various fruits and vegetables. We have shown previously that luteolin reduces HT-29 cell growth by inducing apoptosis and cell cycle arrest. The objective of this study w...

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Bibliographic Details
Main Authors: Lim Do, Cho Han, Kim Jongdai, Nho Chu, Lee Ki, Park Jung
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/12/9