Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt

<p>Abstract</p> <p>Background</p> <p>Previous studies have suggested that peroxisome proliferator activated receptor-gamma (PPAR-γ)-mediated neuroprotection involves inhibition of microglial activation and decreased expression and activity of inducible nitric oxide synt...

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Bibliographic Details
Main Authors: Hunter Randy, Xin Tao, Xing Bin, Bing Guoying
Format: Article
Language:English
Published: BMC 2008-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/5/1/4