Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor
The fatal determination of bone marrow mesenchymal stem/stromal cells (BMSC) is closely associated with mechano-environmental factors in addition to biochemical clues. The aim of this study was to induce osteogenesis in the absence of chemical stimuli using a custom-designed laminar flow bioreactor....
Main Authors: | Shuntaro Yamada, Mohammed Ahmed Yassin, Thomas Schwarz, Jan Hansmann, Kamal Mustafa |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-06-01
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Series: | Journal of Tissue Engineering |
Online Access: | https://doi.org/10.1177/20417314211019375 |
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