Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor

The fatal determination of bone marrow mesenchymal stem/stromal cells (BMSC) is closely associated with mechano-environmental factors in addition to biochemical clues. The aim of this study was to induce osteogenesis in the absence of chemical stimuli using a custom-designed laminar flow bioreactor....

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Bibliographic Details
Main Authors: Shuntaro Yamada, Mohammed Ahmed Yassin, Thomas Schwarz, Jan Hansmann, Kamal Mustafa
Format: Article
Language:English
Published: SAGE Publishing 2021-06-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314211019375