Regioselective Arylation of 1,3-Dimethyllumazine and Its 5-Oxide by Diazonium Salts
A new method to introduce an aryl group directly into the pteridine nucleus by the action of arene diazonium salt in an aqueous alkaline solution is described. 1,3-Dimethyllumazine and benzene diazonium chloride reacts in an aqueous solution at pH 8-9 to give 7 -phenyl-1 ,3-dimethyllumazine together...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
1997-09-01
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Series: | Pteridines |
Subjects: | |
Online Access: | https://doi.org/10.1515/pteridines.1997.8.3.188 |