Regioselective Arylation of 1,3-Dimethyllumazine and Its 5-Oxide by Diazonium Salts

A new method to introduce an aryl group directly into the pteridine nucleus by the action of arene diazonium salt in an aqueous alkaline solution is described. 1,3-Dimethyllumazine and benzene diazonium chloride reacts in an aqueous solution at pH 8-9 to give 7 -phenyl-1 ,3-dimethyllumazine together...

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Bibliographic Details
Main Authors: Sugimoto Takashi, Seo Chihiro, Murata Shizuaki, Pfleiderer Wolfgang
Format: Article
Language:English
Published: De Gruyter 1997-09-01
Series:Pteridines
Subjects:
Online Access:https://doi.org/10.1515/pteridines.1997.8.3.188